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Leo Sioris, PharmD, CEO

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Leo Sioris, PharmD, CEODr. Leo Sioris is the CEO and co-founder of SafetyCall International. He also co-founded and served as Vice President of the PROSAR International Poison Center and was co-founder and former Director of the Minnesota Regional Poison Center and Hazard Information Services. He is a full Professor in the Department of Experimental and Clinical Pharmacology at the College of Pharmacy at University of Minnesota. He is Course Director of Clinical Toxicology and preceptor of numerous residents and fellows in clinical toxicology. Dr. Sioris received a BS in Pharmacy with Distinction from the University of Minnesota in 1975 and his Doctorate in Clinical Pharmacy from Minnesota in 1977. He completed post-graduate training in Clinical Toxicology with the Hennepin Poison Center and the Department of Emergency Medicine, Hennepin County Medical Center (HCMC) and the Minneapolis Medical Research Foundation. Dr. Sioris has presented numerous scientific abstracts and invited presentations, as well as published numerous scientific articles, acted as a peer reviewer, and has been the recipient of numerous grants and contracts. His research interests include clinical toxicology, forensic toxicology, caustics, epidemiology of household and occupational exposures, as well as modeling of the delivery of poison center, post-market surveillance and regulatory reporting and product stewardship services to industry.

Publications

Krenzelok EP, Peterson CD, Sioris LJ: Carbon Monoxide Poisoning. Minnesota Pharmacist, November 1977.

Sioris LJ, Krenzelok EP: Phencyclidine Intoxication: A Literature Review. American Journal of Hospital Pharmacy 35: 1362-1267, November 1978.

Sioris LJ. Petroleum Distillate Poisoning. Minnesota Pharmacist, August 1978.

Sioris LJ. Petroleum Distillate Poisoning: What the Pharmacist Needs to to Know. Tomorrow’s Pharmacist 1:7, February 1978.

Sioris LJ. If Your Child is Poisoned … Child Care Resources, August 1978.

Sioris LJ. Management of Acute Phencyclidine Overdosage. Clinical Toxicology Consultant 2:28-34, April 1980.

Sioris LJ, Weibert B, and Pentel PR: Potentiation of Warfarin Anticoagulation by Sulfisoxazole. Archives of Internal Medicine 3:234-235, October 1980.

Pentel P, Sioris LJ: Incidence of Late Arrhythmias Following Tricyclic Antidepressant Overdose. Clinical Toxicology 18(5):543-548, 1981.

Sioris LJ: Sulfisoxazole Affects Warfarin dosing:, “Clinical Highlights” Department, RN Magazine, March 1981.

Olson DK, Sax L, Gunderson P, Sioris LJ: Pesticide Poisoning Surveillance Through Regional Poison Control Centers. American Journal of Public Health. 81:750-753, 1991

Filandrinos DT, Sioris LJ. Transient elevation of liver function tests following ingestion of black locust seeds. Abstract Vet Human Toxicology 1992;34(4):351.

Wright L, Alsap J, Garrettson LK, King B, Sioris LJ, Woolf A: The OPQ: A Predictor of Recurrent Poisoning Accidents in Young Children. Journal of Veterinary & Human Toxicology 34 (5): 448-552 October, 1992.

Kingston RL, Hall SW, Sioris LJ: Clinical Observations & Medical Outcome in 149 Consecutive Cases of Ingestion of a Sodium Arsenate Containing Ant Killer. Journal of Toxicology/Clinical Toxicology. 31(4):581-591, 1993

Filandrinos DT, Zunker RJ, Sioris LJ. Costs incurred from unnecessary hospital visits if a poison center was unavailable. Abstract Vet Human Toxicology 1993;35(4):323.

Skoglund RS, Roy RR and Sioris LJ: Evaluation of Art and Craft Products for Chronic Toxicity Under ASTM D 4236-88. The Toxicologist, 13(1): 417, 1993

Skoglund RS, Roy RR, Sioris LJ, Hall SW: Medical Center Based Education and Training in Clinical and Applied Toxicology. The International Toxicologist, 1995

Sioris LJ & Bjornson J, Keeping Your Consumers Healthy and Safe: Provide a Check-Up to Maintain Consumer Loyalty, Customer Relationship Management, IV(4):35-37, December 1999

Kingston RL, Chen WL, Borron SW, Sioris LJ, Harris CR, Engebretsen KM, Chlorpyriphos; A Ten-Year U.S. Poison Center Exposure Experience, Journal of Veterinary & Human Toxicology, 41(2):87-92, April 1999

Sioris LJ & Bjornson J, Handling the Hype of Web Hoaxes, Customer Relationship Management, V(4):7-9, December 2000

Sioris LJ, Bjornson J. Customer Health and Safety: A Discussion of Ethics, Customer Relationship Management, VI(3), September 2001

Kingston RL, Sioris LJ. Minnesota Poison Control System Review of Year 2000 Data. Provided to the Commissioner, Minnesota Department of Health. State of Minnesota, St. Paul, MN 2001 (Technical Paper)

Kingston RL, Sioris LJ, & Qualley B, A Survey of Knowledge and Attitudes Concerning Accidental Poisoning in Minnesota, Provided to the Commissioner, Minnesota Department of Health. State of Minnesota, St. Paul, MN 2001 (Technical Paper).

Sioris LJ, Bjornson J. Consumer Privacy-Implications of the New HIPPA Regulations, Customer Relationship Management, November, 2002.

Sioris LJ, Spassova D, LeMaster S, Gualtieri J, Kingston RL, Owens J, A Comparative Outcome Analysis Following Exposure to a Selected Group of Common Household Products, In process.

Letters to the Editor

Sioris LJ, Peterson CD, Krenzelok EP: Acid Ingestion and Neutralizing Agents. Journal of the American College of Emergency Physicians 1979;9:124.

Book Chapters

Sioris LJ. Phencyclidine Overdose. Chapter 13 in Clinical Toxicology of Drugs: Principles and Practice, Ed. Skoutakis V., Published by Lea and Febiger, Philadelphia, 1982.

Sioris LJ. Heavy Metal Poisoning, Textbook of Critical Care Medicine, 5th edition, Edited by Mitchell P. Fink, Published by Saunders, 2005.

Berkner D, Sioris LJ. Echinacea, Herbal Products: Toxicology and Clinical Pharmacology, 2nd Edition, Edited by Tracy, TS and Kingston, RL, Published by Humana Press, Totowa, NJ, 2007.

Sioris LJ, Schuller H. Toxicity of Soaps, Detergents and Bleaches, Haddad & Winchesters’ Clinical Management of Poisoning and Overdose, 4th Edition, Ed. Shannon MW, Burns M, and Borron SW, Elsevier, NY, NY. Published by Saunders Elsevier, Philadelphia, PA, 2007.

Sioris LJ, Haak LE. Hydrofluoric Acid. In Osweiler G, Hovda LR, Brutlag A, Lee JA, eds. Blackwell’s Five-Minute Veterinary Consult Clinical Companion: Small Animal Toxicology. 1st ed. Ames, IO: Wiley-Blackwell. Expected year of publication January 2011.

Sioris LJ, Haak LE. Soaps, Detergents, and Fabric Softeners. In Osweiler G, Hovda LR, Brutlag A, Lee JA, eds. Blackwell’s Five-Minute Veterinary Consult Clinical Companion: Small Animal Toxicology. 1st ed. Ames, IO: Wiley-Blackwell. Expected year of publication January 2011.

Scientific Abstracts

Krenzelok EP, Sioris LJ, Clinton J: Caustic Esophageal and Gastric Erosion Without Evidence of Oral Burns Following Detergent Ingestion. Presented at the 6th Annual American College of Emergency Physicians/EDNA Scientific Assembly, Houston, Texas. September 1978.

Krenzelok EP, Sioris LJ, and Garber RJ: Teaching Poison Prevention to Preschool Children, Their Parents and Professional Educators Through Child Care Centers. Presented at the National Poison Center Network Annual Meeting. Pittsburgh, Pennsylvania. June 1978.

Krenzelok EP, Sioris LJ and Garber RJ: Teaching Poison Prevention to Preschool Children, Their Parents and Professional Educators Through Child Care Centers. Presented at the American Association of Poison Control Centers/AACT Joint Meeting. Chicago, Illinois. October 1978.

Krenzelok EP, Sioris LJ and Garber RJ: Teaching Poison Prevention to Preschool Children, Their Parents and Professional Educators Through Child Care Centers. Presented at the American Society of Hospital Pharmacists Midyear Clinical Meeting. Las Vegas, Nevada. December 1978.

Sioris LJ and Peterson CD: Asymptomatic Acute Arsenic Ingestion. Presented at the joint annual meeting of the American Association of Poison Control Centers/American Academy of Clinical Toxicology/American Board of Medical Toxicology. Minneapolis, Minnesota. August 1980.

Sioris LJ and Guthrie K: Acute Selenium Poisonings. Presented at the Joint Annual Meeting of the American Association of Poison Control Centers/ American Academy of Clinical Toxicology/American Board of Medical Toxicology. Minneapolis, Minnesota. August 1980.

Qualley B, Sioris LJ, Hall SW, Kingston R: Development and Implementation of a Comprehensive Quality Assurance Program for a Poison Center. American Association of Poison Control Centers/American Academy of Clinical Toxicology/American Board of Medical Toxicology Annual Scientific Meeting, Kansas City, Missouri. 1985.

Kingston R, Hall SW, Saxena K, Warren B, and Sioris LJ: Evaluation of a Poison Center Response to a Simulated Chemical Disaster. American Association of Poison Control Centers/American Academy of Clinical Toxicology/American Board of Medical Toxicology Annual Scientific Meeting, Kansas City, Missouri. 1985.

Alden A, Wright B, Olson D, Qualley B, and Sioris LJ: Child Development and Poison Prevention Strategies. American Association of Poison Control Centers/American Academy of Clinical Toxicology/American Board of Medical Toxicology Annual Scientific Meeting, Kansas City, Missouri. 1985.

Sioris LJ, Saxena K, and Nelson N: Gyromitra Mushroom Poisoning. American Association of Poison Control Centers/American Academy of
Clinical Toxicology/American Board of Medical Toxicology Annual Scientific Meeting, Santa Fe, New Mexico. 1986.

Kingston RL, Hall SW, and Sioris LJ: A Survey of Regional Poison Control Centers with an Emphasis on Cost of Services and Source of Revenue. AAPCC/AACT/ABMT Annual Scientific Meeting, Baltimore, MD. 1988.

Kingston RL, Hall SW, and Sioris LJ: Clinical Observations and Medical Outcome in 149 Consecutive Cases of Ingestion of a Sodium Arsenate-Containing Ant Killer. AAPCC/AACT/ABMT/CAPCC Annual Scientific Meeting, Atlanta, GA. 1989.

Kingston RL, Sioris LJ, Mjanger V, Qualley B, and Hall SW: Telemarketing and Direct Mail Fundraising Options for Poison Centers. AAPCC/AACT/ABMT/CAPCC Annual Scientific Meeting, Atlanta, GA. 1989.

Qualley B, Sioris LJ, Hall SW, & Reisdorf J: Survey of 911 Centers to Determine How Poison Calls are Handled. AAPCC/AACT/ABMT/CAPCC Annual Scientific Meeting, Tuscon, AZ. 1990.

Sioris LJ: A Poison Center Based 24-Hour Emergency Response Hotline National Emergency Response Conference Chicago, IL, April 1991.

Kingston R, Sioris LJ: A New Optically Scanned Form For PC Case Documentation. AAPCC/AACT/ABMT/CAPCC Annual Scientific Meeting, Toronto, Ontario, Canada. October 3, 1991.

Kingston R, Saxena K, Sioris LJ, Lelwica T: Alcohol Abuse in a 47-Month-Old Child. AAPCC/AACT/ABMT/CAPCC Annual Scientific Meeting, Toronto, Ontario, Canada. October 4, 1991.

Sioris LJ, Kingston R, Ryan KA: Three Year Follow-Up of a Poison Center Managed In-House Telemarketing Program. AAPCC/AACT/ABMT/CAPCC Annual Scientific Meeting, Toronto, Ontario, Canada. October 3, 1991.

Brueggemann PW, Hall SW, Sioris LJ: Utilization of Computer Spreadsheets in a Comprehensive Quality Assurance Program. AAPCC/AACT/ABMT/CAPCC Annual Scientific Meeting, Toronto, Ontario, Canada. October 3, 1991.

Skoglund RS, Ryan KA, Sioris LJ: Development of an Optically Based Image Management System for the Storage and retrieval of MSDSs in a Poison Center. AAPCC/AACT/ABMT/CAPCC Annual Scientific Meeting, Toronto, Ontario, Canada. October 3, 1991. Abstract Published in Veterinary and Human Toxicology 33(4):378, 1991.

Sioris LJ, Kingston R. A Clinical Pharmacist-Based Emergency Response/Hazard Communication Model for Chemical Manufacturers and Employees. American College of Clinical Pharmacy Winter Research Forum, Phoenix, Arizona. February 11, 1992.

Filandrinos DT, Sioris LJ: Transient Elevation of Liver Function Tests Following Ingestion of Black Locust Seeds. AAPCC/AACT/ABMT/CAPCC Annual Scientific Meeting, Tampa, Florida. September 19-22, 1992. Abstract Published in Veterinary and Human Toxicology 34(4):351, 1992.

Roy RR, Skoglund RS, and Sioris LJ: Evaluation of the Toxicology of Tartrazine (FD&C Yellow No. 5) for Labeling Requirements under ASTM D 4236-88. AAPCC/AACT/ABMT/CAPCC Annual Scientific Meeting, Tampa, Florida. September 19-22, 1992. Abstract Published in Veterinary and Human Toxicology 34(4):357, 1992.

Gruenhagen MS, Kingston RL, Skoglund RS, and Sioris LJ: Product Label 1-800 Phone Numbers for Emergency Medical Product Information. International Congress of Clinical Toxicology, New York, New York, Sept. 10-13, 1993.

Filandrinos DT, Zunker RJ, Sioris LJ: Costs Incurred from Unnecessary Emergency Department Visits for Treatment of Poisonings. International Congress of Clinical Toxicology, New York, New York, Sept. 10-13, 1993. Abstract Published in Veterinary and Human Toxicology 35(4):323, 1993.

Skoglund RS, Roy RR, Sioris LJ. Evaluation of Art and Craft Products for Chronic Toxicity Under ASTM D 4236-88. Society of Toxicology Annual Meeting, New Orleans, Louisiana, 1993.

Gualtieri JF, Sioris LJ. Withdrawal Syndrome in a Child With a History of Chronic Bromfed-PD Use. North American Congress of Clinical Toxicology, Salt Lake City, Utah, Sept. 23, 1994. Abstract Published in Veterinary and Human Toxicology 36:348, 1994.

Filandrinos DT, Sioris LJ. Description of a Statewide Program for Education of Health Care Professionals on the Management of the Poisoned Patient, 7th International Congress of Toxicology, Seattle, Washington, July 5, 1995.

Sioris LJ, Skoglund RS, Kingston RL, Abbott JC, and Ryan KA: The Electronic Poison Center. Presented at the 2nd Meeting of the European Association of Poison Centres and Clinical Toxicologists on Computers as an Aid in Poison Centres, Lille, France, December 6-8, 1995.

Kingston RL, Heidelberger TR, Sioris LJ, and Ryan KA: Computerized On-Line Case Data Form. for Poison Consultation.. Presented at the 2nd Meeting of the European Association of Poison Centres and Clinical Toxicologists on Computers as an Aid in Poison Centres, Lille, France, December 6-8, 1995.

Sioris LJ, Skoglund RS, and Kingston RL: Expansion of the Public Poison Center Model to an Emergency Response, Regulatory Compliance Model for Chemical Manufacturers, Employers, and End-Users. Presented at the National Safety Congress 1995 Annual Meeting, Dallas, Texas, November 3-6, 1995.

Skoglund RS, Roy RR, Sioris LJ, Hall SW: Medical Center Based Education and Training in Clinical and Applied Toxicology, 7th International Congress of Toxicology, Seattle, Washington, July 5, 1995.

Sioris LJ. A Comprehensive Toxicology Information Center: Status of a New Service Paradigm, National Congress of Clinical Toxicology, Romanian Academy-Medical Sciences Department, Bucharest, Romania, November 13-15, 1996.

Page B, Plewe S, Osimitz T, Manderfield C, Sioris L, Kingston R. Comparison of Exposures Reported To AAPCC and Exposures Reported to a Contract PCC, North American Congress of Clinical Toxicology, Portland, Oregon, Oct. 12-15, 1996.

Sioris LJ, Kingston RL, Skoglund RS. The Use of an Enhanced Public Poison center Model as Part of a Comprehensive Chemical Hazard Communication Program, Society for Chemical Hazard Communication, San Diego, CA, April 29, 1997.

McGee M, Gualtieri J, Sioris LJ. Doxylamine-Related Homicide, National Association of Medical Examiners Annual Meeting, Minneapolis, MN, October 18, 1999.

Kingston RL, Sioris LJ, Borron SW, Online Access to Postmarket Surveillance Incident Data, Presented at the 3rd International Meeting of Computers in Toxicology Symposia, Sponsored by the European Association of Poison Centres and Clinical Toxicologists, Lille, France, December 2000.

Borron SW, Kingston RL, Sioris LJ; Mass Psychogenic Illness in the Era of Chemical Terrorism: Implications for Poison Centers, European Association of Poison Control Centers Annual Meeting, Lille, France, 2005