Alternate names

cardiac medication, angiotensin-converting enzyme inhibitor, enalapril, captopril, lisinopril, ramipril, imidapril, benazepril, Enacard, Lotensin, Capoten, Vasotec, Prinivel, Zestril

Toxicity to pets

Angiotensin-converting enzyme (“ACE”) inhibitors are common cardiac medications used in both human and veterinary medicine to treat heart disease and hypertension (high blood pressure). When accidentally ingested in poisonous amounts by pets, ACE inhibitors can result in hypotension (low blood pressure), lethargy, weakness, vomiting, and diarrhea. Pets with underlying medical problems (e.g., kidney failure, heart disease, etc.) can be more sensitive to the effects of these medications.

  • Vomiting
  • Diarrhea
  • Low blood pressure
  • Lethargy
  • Weakness
  • Excessive drinking or urination
  • Collapse


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The content of this page is not veterinary advice. A number of factors (amount of substance ingested, size of the animal, allergies, etc.) determine what is toxic to a particular pet. If you think your pet has eaten something potentially toxic, call Pet Poison Helpline or seek immediate veterinary treatment.