Toxicity to pets

This plant, which is a spreading ground cover, is also commonly known as the Indian Apple, American Mandrake or Umbrella Leaf. This plant contains the toxin podopyllotoxin, a glycoside, that is easily absorbed through tissue. When pets accidentally ingest or contact this plant, Mayapple can result in both gastrointestinal (e.g., vomiting, diarrhea, drooling) and dermal irritation.