Dogs will sometimes need medication, just like people, but their internal systems are different from ours, so it is important to know which medications are safe for our pets. Dogs can take Lexapro but cannot take acetaminophen. Lexapro is an anti-depressant medication that can address separation anxiety, or any other anxiety disorders your dog may experience. Lexapro is a prescription-only medication. Acetaminophen is the main ingredient in Tylenol, which is used to treat fever or pain. Never give your dog acetaminophen if they are experiencing pain or a fever. There are dog-friendly pain medications that your vet can prescribe. Always consult your veterinarian before administering any medications to your pet.

Clinical Signs of Lexapro and Acetaminophen Poisoning

Lexapro is not a commonly prescribed medication, because of the potential dangers of an overdose. There are other anxiety medication options. Alternatively, contact a dog trainer if your dog is experiencing separation anxiety. Symptoms of a Lexapro overdose include:

  • Sedation
  • Incoordination
  • Elevated heart rate 
  • Elevated blood pressure
  • Tremors
  • Seizures


Dogs can experience acetaminophen poisoning if they consume acetaminophen. Dogs should not consume any acetaminophen because it is highly dangerous to dogs. Below are the most common clinical signs of acetaminophen poisoning: 

  • Severe liver damage 
  • Gray colored gums 
  • Labored breathing 
  • Vomiting 

Keep all human and dog medications in a secure location. Dogs can eat through medicine bottles and mistake pills for treats. Have one person in charge of all canine medications. 

Treatment for Lexapro and Acetaminophen Poisoning

It is extremely important to receive medical care as soon as possible if you suspect your pet is experiencing poisoning from either Lexapro or acetaminophen. Your dog may be behaving abnormally if they have been poisoned. Your vet will assess your pet once you arrive at the clinic. Various medications may be used to address the existing symptoms. Your dog may be kept overnight if the symptoms cannot be controlled. Call Pet Poison Helpline® at (855) 764-7661 or your vet with any questions or concerns.