Understanding the Symptoms and Treatment for Ivermectin-Sensitive Dogs 

If you’re a pet owner, you may have come across the term “Ivermectin-sensitive” and wondered what it means. Ivermectin is commonly prescribed for dogs and cats with parasitic infections or as a preventive measure against heartworms. Although generally safe for pets, it is important to note that there are certain risks associated with its use. Certain dog breeds are born with a genetic mutation that makes them more sensitive to Ivermectin. Thankfully, with a better understanding of the signs and symptoms associated with Ivermectin sensitivity, you can keep your beloved companion safe.  

Ivermectin Toxicity 

Symptoms of Ivermectin poisoning can range from mild to severe. After ingestion, initial symptoms can begin to develop within 4 to 12 hours, while more gradual clinical signs may take up to 2 or 3 days to appear. Ivermectin can cause neurological damage and potential seizures. Common signs to watch out for include: 

  • Seizures  
  • Coma  
  • Disorientation  
  • Drooling  
  • Tremors  
  • Dilated pupils  
  • Difficulty walking   
  • Trouble breathing  

Dog Breeds That Are Sensitive to Ivermectin  

Typically, the rule of thumb with Ivermectin treatment is: “white feet, do not treat”.Below is a list of dog breeds that can be sensitive to Ivermectin: 

  • Australian Sheperd  
  • Border Collie 
  • German Sheperd 
  • Miniature American Sheperd  
  • Old English Sheepdog  
  • Shetland Sheepdog  
  • Skye Terrier 


If your dog is having an adverse reaction to Ivermectin, you must contact your veterinarian and Pet Poison Helpline at (855) 764-7661 immediately. Your veterinarian and Pet Poison Helpline can provide any necessary medical advice. Without prompt and aggressive treatment, Ivermectin poisoning can be fatal. Transport your dog to the veterinary clinic right away for emergency treatment. After an examination, your veterinarian will determine an appropriate treatment plan. Possible treatment may include inducing vomiting and administrated activated charcoal to bind to the toxins. You can be rest assured that your pup is in safe hands.